<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Samira. Fetni</style></author><author><style face="normal" font="default" size="100%">Nabil Bertella</style></author><author><style face="normal" font="default" size="100%">Ammar Ouahab</style></author><author><style face="normal" font="default" size="100%">Jose Miguel Martinez Zapater</style></author><author><style face="normal" font="default" size="100%">Sonia De Pascual-Teresa Fernandez</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Composition and biological activity of the Algerian plant Rosa canina L. by HPLC-UV-MS</style></title><secondary-title><style face="normal" font="default" size="100%">Arabian Journal of Chemistry</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2020</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%">https://www.sciencedirect.com/science/article/pii/S187853521730182X</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">1105-1119</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p id=&quot;sp0005&quot; style=&quot;text-align: justify;&quot;&gt;
	The present study was carried out in order to identify and characterize the compounds of&amp;nbsp;&lt;em&gt;Rosa canina&lt;/em&gt;&amp;nbsp;fruits by HPLC-UV-MS. The total phenolic determiner by a new Fast Blue method (FBBB), which detects phenolic directly, reported an average total phenolic concentration of 1.7 folds greater than Folin-Ciocalteu (F-C), which indicates that an indirect detection method of total phenolic should be replaced in future studies by the FBBB method. TPC of the ethanolic extract was positively correlated with 1,1-diphenyl-2-picryl-hydrazyl (DPPH) free radical scavenging effect. The DPPH activity of&amp;nbsp;&lt;em&gt;R. canina&lt;/em&gt;&amp;nbsp;extract which is higher than the IC&lt;sub&gt;50&lt;/sub&gt;&amp;nbsp;of the ascorbic acid and Butylated Hydroxytoluene (BHT), but lower than the IC&lt;sub&gt;50&lt;/sub&gt;&amp;nbsp;of quercetin and trolox. The determination of intracellular reactive oxygen species (ROS) proved the antioxidant effect of the extract on HepG2 and SH-SY5Y cells. A concentration of 1.63 μg/ml on HepG2 cells had an oxidizing effect instead of the antioxidant effect, which is due to the existence of a tert-butyl group in sesquiterpene identified by HPLC-UV-MS method. These results indicate that the fruits of&amp;nbsp;&lt;em&gt;R. canina&lt;/em&gt;&amp;nbsp;can be used as a natural source of antioxidants against oxidative stress and some types of cancer.
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&lt;p style=&quot;text-align: justify;&quot;&gt;
	Ethanolic extract, HPLC-UV-MS,&amp;nbsp;Antioxidant activity,&amp;nbsp;Oxidant effect,&amp;nbsp;Bilobalide A
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</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue></record></records></xml>