<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">DAIKH Badis</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Comparative study of the therapeutic efficacy of autologousplatelet-rich plasma and honey in healing skin wounds in sheep</style></title><secondary-title><style face="normal" font="default" size="100%">veterinary wourd</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2021</style></year></dates><volume><style face="normal" font="default" size="100%">14</style></volume><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">Background and Aim: This investigation is the continuation of a published preliminary study examining the therapeutic&lt;br&gt;efficacy of platelet-rich plasma (PRP) as a topical treatment for skin wounds in sheep. The study aimed to compare the&lt;br&gt;healing effects of autologous PRP with that of natural honey.&lt;br&gt;Materials and Methods: This study involved nine clinically healthy male sheep. After sterile skin preparation, fullthickness&lt;br&gt;longitudinal incision wounds were created on the backs of each animal. The animals were randomly divided into&lt;br&gt;three groups of three sheep each. In Group I, the wounds were treated with PRP; in Group II, the wounds were treated with&lt;br&gt;honey; and in Group III, the wounds were treated with saline solution. The different treatments were administered topically&lt;br&gt;every 3 days. Healing was assessed by a semi-quantitative histopathological study from biopsies taken on the 3rd, 7th, 14th,&lt;br&gt;21st, and 28th days of healing. The data obtained were compared using the non-parametric Mann–Whitney U-test, and p&amp;lt;0.05&lt;br&gt;and 0.01 were used to determine the level of significance of the recorded differences.&lt;br&gt;Results: Semi-quantitative histopathological evaluation showed significant differences in the progression of wound healing&lt;br&gt;between the three study groups. Recorded data showed that PRP may reduce inflammation during the first 3 days after the&lt;br&gt;incision. Moreover, the synthesis and organization of collagen fibers were significantly improved in the group treated with&lt;br&gt;PRP compared with those in the group treated with honey.&lt;br&gt;Conclusion: PRP offers a promising therapeutic option for healing skin wounds in sheep compared with honey.&lt;br&gt;Keywords: honey, platelet-rich plasma, sheep, skin, wound healing.</style></abstract><issue><style face="normal" font="default" size="100%">8</style></issue></record></records></xml>