<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">deffa ouafa</style></author><author><style face="normal" font="default" size="100%">DAIKH Badis</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Histological assessment of topical mixture of Thymus vulgarishoney and Nigella sativa L seed powder on skin wound healingin sheep</style></title><secondary-title><style face="normal" font="default" size="100%">international of biosciences </style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2022</style></year></dates><volume><style face="normal" font="default" size="100%">21</style></volume><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">Honey and Nigella sativa L has been known for millennia of years for its therapeutic healing properties. This&lt;br&gt;present histopathological study aims to evaluate the healing activity of Algerian bee honey derived from the&lt;br&gt;nectar of Thymus vulgaris mixed with N. sativa seed powder on a sheep model. Induction of wounds with&lt;br&gt;longitudinal incisions of full thickness, was carried out in the dorsal part of 09 healthy sheep belonging to the&lt;br&gt;animal facility of the veterinary department of the University of Batna 1. After inductions of the wounds, the&lt;br&gt;animals were distributed to the randomly in 03 batches of animals of 03 sheep for each with appropriate topical&lt;br&gt;care for each batch: the batch of animals treated with Thymus vulgaris honey mixed with N. sativa seed powder&lt;br&gt;(HNS), the Madicassol batch and the Vaseline. The topical application of the various treatments was carried out&lt;br&gt;once a day for 02 successive weeks. Histopathological evaluation was performed by measuring scar tissue&lt;br&gt;thickness. In the batch of animals treated with HNS mixture, the thickness of the scar tissues revealed a&lt;br&gt;significant decrease compared to the Madicassol and Vaseline batches. No keloid or detectable in the wounds of&lt;br&gt;the mixture HNS lot. The results of this experimental study suggested that the topical use of local honey from the&lt;br&gt;nectar of T.vulgaris mixed with N. sativa seed powder significantly reduced the thickness of wound healing in&lt;br&gt;sheep.</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue></record></records></xml>