Rachid AYACHE, Hassina HARKAT, Lamiss A, Abderezzak BO.
Study of 14-Substituted-14H-Dibenzo[a,j] Xanthene Derivatives. Journal of Molecular and Engineering Materials [Internet]. In Press.
Publisher's VersionAbstractXanthene derivatives of the 14-aryl-14H dibenzo[a.j] xanthene type were exploited in our study because of their interesting biological profile as well as their innumerable applications described in previous studies. They were synthesized by one-pot condensation of β�-naphthol with arylaldehydes and catalyzed by zinc trifluoromethanesulfate Zn(OTf)2 under conventional heating without solvent. Their characterization was carried out by Ultraviolet–Visible spectrophotometry (UV–Vis), Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD) and scanning electron microscopy (SEM). First, spectral analysis in the UV–Vis range showed that all xanthene derivatives had similar absorption spectra at an absorption maximum (λmax)(�max) in the region of 310–340nm. Similarly, the infrared spectra suggested the presence of characteristic bands for each product in the range of 500–3500cm−1−1. In addition, the analysis of their crystalline structures was carried out by the XRD technique and reported in our study. Finally, their sizes and morphologies were highlighted by SEM. The obtained results revealed the presence of microcrystals in the form of micro-cubes having an average length of 10μ�m for the compound C2727H1818O and micro-shuttles of average size of 20μ�m for the compound C2727H1717BrO. It was therefore concluded that the xanthene derivatives synthesized have characteristic functional groups and structures which will provide them with various therapeutic properties and can therefore be exploited as bioactive molecules in several fields.
