The current study focuses on the chemical composition, and evaluation of antioxidant and antibacterial activity of the aerial parts of Centaurea resupinata subsp. dufourii. Using different chromatographic methods nine compounds 1–9 were isolated. The structural identification of isolated compounds was achieved using several spectroscopic methods NMR techniques (1H NMR, 13C NMR, COSY, HSQC, HMBC) and mass spectroscopy (ESI-MS) and by comparison with literature data. The structures of these compounds were identified as nicotiflorin (1), apigetrin (2), chrysoeriol (3), apigenin (4), chrysin (5), daucosterol (6), β-sitosterol (7), taraxastrerol (8) and lupeol (9). The antibacterial and antioxidant activities of ethyl acetate and n-butanol extracts have been evaluated. The antioxidant activity was assessed in vitro using DPPH radical scavenging method, which showed that ethyl acetate extract possessed an interesting antioxidant potential (IC50 = 36.263 ± 0.005 μg/mL).
The phytochemical profile obtained from LC-ESI-MS/MS analysis of the n-butanol extract (BEHL) from the North African endemic plant Hyacinthoides lingulata (Poir.) Rothm. brought about the identification of ten glycosylated derivatives of apigenin and luteolin flavones. For the same plant extract, in vitro anti-inflammatory (hypotonic induced hemolysis and heat induced haemolysis assay) and antioxidant (DPPH and β-Carotene) activities were evaluated observing high inflammatory inhibition by protecting membrane stability of erythrocyte in both heat (84.70 ± 0.24%) and hypotonic induced hemolysis (79.45 ± 0.12%). A remarkable hemostatic effect was also established by measuring the coagulation time (15.95 ± 1.05 s at a dose of 1 mg/mL) of decalcified plasma related to its phytochemical content. It is the first report on combined chemical components and biological evaluation of this specific plant.
A recent study from GLOBOCAN disclosed that during 2018 two million women worldwide had been diagnosed with breast cancer. Currently, mammography, magnetic resonance imaging, ultrasound, and biopsies are the main screening techniques, which require either, expensive devices or personal qualified; but some countries still lack access due to economic, social, or cultural issues. As an alternative diagnosis methodology for breast cancer, this study presents a computer-aided diagnosis system based on convolutional neural networks (CNN) using thermal images. We demonstrate that CNNs are faster, reliable and robust when compared with different techniques. We study the influence of data pre-processing, data augmentation and database size on several CAD models. Among the 57 patients database, our CNN models obtained a higher accuracy (92%) and F1-score (92%) that outperforms several state-of-the-art architectures such as ResNet50, SeResNet50, and Inception. This study exhibits that a CAD system that implements data-augmentation techniques reach identical performance metrics in comparison with a system that uses a bigger database (up to 33%) but without data-augmentation. Finally, this study proposes a computer-aided system for breast cancer diagnosis but also, it stands as baseline research on the influence of data-augmentation and database size for breast cancer diagnosis from thermal images with CNNs
A recent study from GLOBOCAN disclosed that during 2018 two million women worldwide had been diagnosed with breast cancer. Currently, mammography, magnetic resonance imaging, ultrasound, and biopsies are the main screening techniques, which require either, expensive devices or personal qualified; but some countries still lack access due to economic, social, or cultural issues. As an alternative diagnosis methodology for breast cancer, this study presents a computer-aided diagnosis system based on convolutional neural networks (CNN) using thermal images. We demonstrate that CNNs are faster, reliable and robust when compared with different techniques. We study the influence of data pre-processing, data augmentation and database size on several CAD models. Among the 57 patients database, our CNN models obtained a higher accuracy (92%) and F1-score (92%) that outperforms several state-of-the-art architectures such as ResNet50, SeResNet50, and Inception. This study exhibits that a CAD system that implements data-augmentation techniques reach identical performance metrics in comparison with a system that uses a bigger database (up to 33%) but without data-augmentation. Finally, this study proposes a computer-aided system for breast cancer diagnosis but also, it stands as baseline research on the influence of data-augmentation and database size for breast cancer diagnosis from thermal images with CNNs
Cet article est consacré à l’étude des performances de la génératrice asynchrone à cage double étoile (GASDE) en site isolé. Le système de commande est composé d’une GASDE raccordé à un bus continu et une charge en sortie de deux redresseurs à commande MLI. Une étude comparative entre la technique de commande conventionnelle et la commande adaptée basée sur l’introduction de la SVM-PI-flou et un nouvel estimateur de flux (flux virtuel statorique) afin d’améliorer la qualité d’énergie et d’atténuer les harmoniques du courant.
Cet article est consacré à l’étude des performances de la génératrice asynchrone à cage double étoile (GASDE) en site isolé. Le système de commande est composé d’une GASDE raccordé à un bus continu et une charge en sortie de deux redresseurs à commande MLI. Une étude comparative entre la technique de commande conventionnelle et la commande adaptée basée sur l’introduction de la SVM-PI-flou et un nouvel estimateur de flux (flux virtuel statorique) afin d’améliorer la qualité d’énergie et d’atténuer les harmoniques du courant
Cet article est consacré à l’étude des performances de la génératrice asynchrone à cage double étoile (GASDE) en site isolé. Le système de commande est composé d’une GASDE raccordé à un bus continu et une charge en sortie de deux redresseurs à commande MLI. Une étude comparative entre la technique de commande conventionnelle et la commande adaptée basée sur l’introduction de la SVM-PI-flou et un nouvel estimateur de flux (flux virtuel statorique) afin d’améliorer la qualité d’énergie et d’atténuer les harmoniques du courant.
Coronavirus disease has become a worldwide threat affecting almost every country in the world. The spread of the virus is likely to continue unabated. The aim of this study is to compare between Autoregressive Integrated Moving Average (ARIMA) model, Fuzzy time series and Holt-Winters – No seasonal for forecasting the COVID-19 new cases in Algeria. Methods: Three different models to predict the number of Covid-19 new cases in Algeria were used. The number of new cases of COVID-19 in Algeria during the period from 24th February 2020 to 31th July 2021 was modeled according to ARIMA(4,1,2) model, Five based Fuzzy time series models including the Chen model, Heuristic Huareng model, Singh model, Abbasov-Manedova model and NFTS model, and Holt-Winters – No seasonal. Results: The predictive values were obtained from the 1st August 2021 to 31th December 2021. According to a set of criteria (ME, MAE, MSE, RMSE, U), we found that the FTNS model is the most accurate and best generating model for the values of the number of new cases of Covid-19. Conclusion: To the best of our knowledge, this is the first comparative study of three models of forecasting of Covid-19 new cases in Algeria. This study shows that ARIMA models with optimally selected covariates are useful tools for monitoring and predicting trends of COVID-19 cases in Algeria. Moreover, this forecast will help the Health authorities to be better prepared to fight the epidemic by engaging their healthcare facilities.
Background: Coronavirus disease has become a worldwide threat affecting almost every country in the world. The spread of the virus is likely to continue unabated. The aim of this study is to compare between Autoregressive Integrated Moving Average (ARIMA) model, Fuzzy time series and Holt-Winters – No seasonal for forecasting the COVID-19 new cases in Algeria.
Methods: Three different models to predict the number of Covid-19 new cases in Algeria were used. The number of new cases of COVID-19 in Algeria during the period from 24th February 2020 to 31th July 2021 was modeled according to ARIMA(4,1,2) model, Five based Fuzzy time series models including the Chen model, Heuristic Huareng model, Singh model, Abbasov-Manedova model and NFTS model, and Holt-Winters – No seasonal.
Results: The predictive values were obtained from the 1st August 2021 to 31th December 2021. According to a set of criteria (ME, MAE, MSE, RMSE, U), we found that the FTNS model is the most accurate and best generating model for the values of the number of new cases of Covid-19.
Conclusion: To the best of our knowledge, this is the first comparative study of three models of forecasting of Covid-19 new cases in Algeria. This study shows that ARIMA models with optimally selected covariates are useful tools for monitoring and predicting trends of COVID-19 cases in Algeria. Moreover, this forecast will help the Health authorities to be better prepared to fight the epidemic by engaging their healthcare facilities.
A comparative study between a set of chosen machine learning tools for direct remaining useful life prediction is presented in this work. The main objective of this study is to select the appropriate prediction tool for health estimation of aircraft engines for future uses. The training algorithms are evaluated using “time-varying” data retrieved from Commercial Modular Aero-Propulsion System Simulation (C-MAPSS) developed by NASA. The training and testing processes of each algorithm are carried out under the same circumstances using the similar initial condition and evaluation sets. The results prove that among the studied training tools, Support vector machine (SVM) achieved the best results.
A comparative study between a set of chosen machine learning tools for direct remaining useful life prediction is presented in this work. The main objective of this study is to select the appropriate prediction tool for health estimation of aircraft engines for future uses. The training algorithms are evaluated using “time-varying” data retrieved from Commercial Modular Aero-Propulsion System Simulation (C-MAPSS) developed by NASA. The training and testing processes of each algorithm are carried out under the same circumstances using the similar initial condition and evaluation sets. The results prove that among the studied training tools, Support vector machine (SVM) achieved the best results.
: In this paper, we have studied a different fault tolerant control (FTC) strategies for a three-phase induction motor (3p-IM). Further we introduce Backstepping controller (BC) and Input-output linearization controller (IOLC). To provide a direct comparison between these FTCs approaches, the performances are evaluated using the control of 3p-IM under failures, variable speed, and variable parameters. A comparison between the two control strategies is proposed to prove the most robust one. The simulation results show the robustness and good performance of the fault tolerant control with Input-output linearization controller compared to one with Backstepping controller. The FTC with IOLC is more stable and robust against failures, load torque perturbation and speed reversion
The current paper illustrates the numerical study of the global combustion parameters. It mainly focused on the computational analysis that investigated the non-premixed combustion in the cylindrical burner. Therefore, we selected many fuels to supply the burner like Algerian biogas, CH4, C3H8, H2, natural gas, and diesel to compare their aerothermochemical characteristics variables. At first, we applied the numerical methods that confirm the solution convergence like combustion models and grid selection. After that, we resolved the aerothermochemical set equations of combustion using the coupled k-ɛɛ turbulent dynamic model with the probability density function approach. These models are also used to surmount the closer in the set of combustion equations too. Moreover, we integrated the pollutant computation model based on the chemical reactions of NO production. Thus, we evaluated each considered fuel’s NO emission during all combustion fuels cases. Accordingly, the results show that Algerian biogas and hydrogen have special characteristics compared to other cases of fuels. The most prominent characteristics are: the high level of the mixture and burn relative to other fuels, their low pollutants emissions (CO and NO), and the proportional relationship between the OH and NO production. Consequently, biogas and H2 conserve the impact on energy and the environment.
Background and Aim: This investigation is the continuation of a published preliminary study examining the therapeutic efficacy of platelet-rich plasma (PRP) as a topical treatment for skin wounds in sheep. The study aimed to compare the healing effects of autologous PRP with that of natural honey. Materials and Methods: This study involved nine clinically healthy male sheep. After sterile skin preparation, fullthickness longitudinal incision wounds were created on the backs of each animal. The animals were randomly divided into three groups of three sheep each. In Group I, the wounds were treated with PRP; in Group II, the wounds were treated with honey; and in Group III, the wounds were treated with saline solution. The different treatments were administered topically every 3 days. Healing was assessed by a semi-quantitative histopathological study from biopsies taken on the 3rd, 7th, 14th, 21st, and 28th days of healing. The data obtained were compared using the non-parametric Mann–Whitney U-test, and p<0.05 and 0.01 were used to determine the level of significance of the recorded differences. Results: Semi-quantitative histopathological evaluation showed significant differences in the progression of wound healing between the three study groups. Recorded data showed that PRP may reduce inflammation during the first 3 days after the incision. Moreover, the synthesis and organization of collagen fibers were significantly improved in the group treated with PRP compared with those in the group treated with honey. Conclusion: PRP offers a promising therapeutic option for healing skin wounds in sheep compared with honey. Keywords: honey, platelet-rich plasma, sheep, skin, wound healing.
In this paper, we consider a time-fractional reaction-diffusion system with the same nonlinearities of the Newton-Leipnik chaotic system. Through analytical tools and numerical results, we derive sufficient conditions for the asymptotic stability of the proposed model and show the existence of chaos. We also propose a nonlinear synchronization controller for a pair of systems and establish the local and global asymptotic convergence of the trajectories by means of fractional stability theory and the Lyapunov method.
In the industry, automated inspection is important for ensuring the high quality and allows acceleration of procedures for quality control of parts or mechanical assemblies. Although significant progress has been made in precision machining of complex surfaces, precision inspection of such surfaces remains a difficult problem. Thus the problem of the conformity of the parts of complex geometry is felt more and more. Motivated by the need to increase quality and reduce costs, and supported by the progress made in the field of it as well as the automation of production which in recent years has seen a considerable evolution in all these stages: from design to control through manufacturing. Due to, we used a 3D computer aided inspection technique on a physical gear using a coordinate measuring machine equipped with a “PC-DMIS” measurement and inspection software. Our work consists in developing a procedure for inspection for reproduction of gear profile by reconstruction of a circle involute gear from a cloud point’s measurement. In order to obtain a reliable result. In this works, we design the CAD-model of the part as accurately as possible (using a mathematical model) and matched with the 3D points cloud that represents the measurement that obtained from scanner. we compare the measurement cloud points from coordinate measurement machine with the mathematical model of construction by ICP (Iterative Closest Point) methods in order to obtain a conformed result and to show the impact of the dimensional inspection and geometric.
In the industry, automated inspection is important for ensuring the high quality and allows acceleration of procedures for quality control of parts or mechanical assemblies. Although significant progress has been made in precision machining of complex surfaces, precision inspection of such surfaces remains a difficult problem. Thus the problem of the conformity of the parts of complex geometry is felt more and more. Motivated by the need to increase quality and reduce costs, and supported by the progress made in the field of it as well as the automation of production which in recent years has seen a considerable evolution in all these stages: from design to control through manufacturing. Due to, we used a 3D computer aided inspection technique on a physical gear using a coordinate measuring machine equipped with a “PC-DMIS” measurement and inspection software. Our work consists in developing a procedure for inspection for reproduction of gear profile by reconstruction of a circle involute gear from a cloud point’s measurement. In order to obtain a reliable result. In this works, we design the CAD-model of the part as accurately as possible (using a mathematical model) and matched with the 3D points cloud that represents the measurement that obtained from scanner. we compare the measurement cloud points from coordinate measurement machine with the mathematical model of construction by ICP (Iterative Closest Point) methods in order to obtain a conformed result and to show the impact of the dimensional inspection and geometric.
